Universidade Federal do Rio de Janeiro Faculdade de Farmácia


1. Spitz, G.A.; Furtado, C.M.; Sola-Penna, M.; ZANCAN, P. Acetylsalicylic acid and salicylic acid decrease tumor cell viability and glucose metabolism modulating 6-phosphofructo-1-kinase structure and activity. Biochemical Pharmacology, in press, 2008.

2. ZANCAN, P.; Marinho-Carvalho, M.M.; Faber-Barata, J.; Dellias, J.M.; Sola-Penna, M. ATP and fructose-2,6-bisphosphate regulate skeletal muscle 6-phosphofructo-1-kinase altering its quaternary structure. IUBMB Life (London), 60(8): 526–533, 2008. 

3. Rennó, M.; Barbosa, G.; ZANCAN, P.; Veiga, V.; Alviano, C.; Sola-Penna, M.; Menezes, F.; Holandino, C. Crude ethanolic extract from babassu (Orbignya speciosa): cytotoxicity on tumoral and non-tumoral cell lines. Anais da Academia Brasileira de Ciências, 80(3): 467-476, 2008. 

4. ZANCAN, P.; Rosas, A.O.; Marcondes, M.C.; Marinho-Carvalho, M.M.; Sola-Penna, M. Clotrimazole inhibits and modulates heterologous association of the key glycolytic enzyme 6-phosphofructo-1-kinase. Biochemical Pharmacology, 73: 1520-1527, 2007.

5. Leite, T.C.; da Silva, D.; Coelho, R.G.; ZANCAN, P.; Sola-Penna, M. Lactate favors the dissociation of skeletal muscle 6-phophofructo-1-kinase tetramers down-regulating the enzyme and muscle glycolysis. Biochemical Journal (London), 408:123-130, 2007. 

6. ZANCAN, P.; Almeida, F.V.R.; Faber-Barata, J.; Dellias, J.M.; Sola-Penna, M. Fructose-2,6-bisphosphate counteracts guanidinium chloride-, thermal- and ATP-induced dissociation of skeletal muscle key glycolytic enzyme 6-phosphofructo-1-kinase: a structural mechanism for PFK allosteric regulation. Archives of Biochemistry and Biophysics, 467: 275-282, 2007. 

7. ZANCAN, P.; Sola-Penna, M. Modulation of 6-phosphofructo-1-kinase oligomeric equilibrium by calmodulin: formation of active dimmers. Molecular Genetics and Metabolism, 87: 253-261, 2006. 

8. ZANCAN, P.; Sola-Penna, M. Regulation of human erythrocytes metabolism by insulin: cellular distribution of 6-phosphofructo-1-kinase and its implications to red blood cells functions. Molecular Genetics and Metabolism, 86: 401-411, 2005. 

9. ZANCAN, P.; Sola-Penna, M. Calcium influx: a possible role for insulin modulation of intracellular distribution and activity of 6-fosfofructo-1-kinase in human erythrocytes. Molecular Genetics and Metabolism, 86: 392-400, 2005. 

10. ZANCAN, P.; Sola-Penna, M. Trehalose and Glycerol stabilize and renature yeast inorganic pyrophosphatase inactivated by very high temperatures. Archives of Biochemistry and Biophysics, 444: 52-60, 2005. 

11. ZANCAN, P.; Mourão, P.A.S. Venous and arterial thrombosis in rat models: dissociation of the antithrombotic effects of glycosaminoglycans. Blood Coagulation & Fibrinolysis, 15: 45-54, 2004. 

12. Vicente, C.P.; ZANCAN, P.; Peixoto, L.; Sá, R.A.; Araújo, F.; Mourão, P.A.S.; Pavão, M.S.G. Unbalanced effects of dermatan sulfate with different sulfation patterns on coagulation, thrombosis and bleeding. Journal of the International Society on Thrombosis and Haemostasis, 86: 1215-1220, 2001. 

13. Pacheco, R.G.; Vicente, C.P.; ZANCAN, P.; Mourão, P.A.S. Different antithrombotic mechanisms among glycosaminoglycans revealed with a new fucosylated chondroitin sulfate from echinoderm. Blood Coagulation And Fibrinolysis, 11: 563-573, 2000.